LeukemiaHead DR, Boxer LA, Bolyard AA, Dale DC (1999). Blood 94 (10): 430a ‹ Monosomy 7 and activating RAS mutations accompany malignant transformation in patients with congenital neutropenia (CN) treated with recombinant human granulocyte colony stimulating factor (rh-G-CSF) up Mutations in the gene encoding neutrophil elastase (ELA2) are not sufficient to cause congenital neutropenia ›